Breast carcinosarcoma: Clinical and pathological features

Subtitle:

Article type: Case Report

Authors: Mele, Marco^{a; *} | Jensen, Lisbeth L.^b | Vahl, Pernille^b | Funder, Jonas Amstrup^a

Affiliations: [a] Breast and Endocrinal Surgery Department, Aarhus University Hospital, Aarhus, Denmark | [b] Department of Pathology, Aarhus University Hospital, Aarhus, Denmark

Correspondence: [*] Corresponding author: Marco Mele, Breast and Endocrinal Surgery Department, Aarhus University Hospital, Aarhus, Denmark. E-mail:[email protected]

Abstract: Carcinosarcoma of the breast is an extremely rare and highly aggressive breast tumor. It has two distinct malignant cell lines involving epithelial (carcinomatous) and mesenchymal (sarcomatous) components. The literature on the topic is sparse. We report a rare case of carcinosarcoma of the breast containing a small fraction of a pancytokeratin positive sarcomatous-appearing cell population i.e. a metaplastic cell population. The patient was treated with a multidisciplinary approach.

Keywords: Breast carcinosarcoma

DOI: 10.3233/BD-150402

Journal: Breast Disease, vol. 35, no. 3, pp. 211-215, 2015