Affiliations: [a] Department of Surgery, Keio University School of Medicine, Tokyo, Japan | [b] Department of Breast Surgery, Saitama Medical Center, Saitama, Japan | [c] Department of Orthopedics, Saitama Medical Center, Saitama, Japan | [d] Department of Anesthesiology, Saitama Medical Center, Saitama, Japan | [e] Department of Pathology, Saitama Medical Center, Saitama, Japan
Correspondence:
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Corresponding authors: Naohiko Oki, Department of Surgery, Keio University School of Medicine, Tokyo, Japan. E-mail: [email protected]. Hirohito Seki, Department of Breast Surgery, Saitama Medical Center, 4-9-3 Kitaurawa, Urawa-ku, Saitama-city, Saitama, 330-0074, Japan. Tel.: +81 488324951; Ext: 1866; Fax: +81 488337527; E-mail: [email protected]
Abstract: The rate of metastasis to the central nervous system is high in human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer patients. Metastatic cauda equina tumors are characterized by rapid progression of symptoms, thus signifying the requirement of their early treatment. However, these tumors are rarely reported, and their optimal treatment options have not been established yet. Here, we report a case study of a patient with HER2-positive breast cancer that metastasized to the cauda equina. The patient underwent urgent surgery to relieve the spinal cord compression. The pain in her back and lower limbs was greatly reduced. Unfortunately, her ability to walk did not improve sufficiently. Overall, surgical treatment may be a favorable option to improve a patient’s quality of life.
Keywords: Metastatic breast cancer, intramedullary spinal cord metastasis, cauda equina tumor, brain metastasis, human epidermal growth factor receptor 2
DOI: 10.3233/BD-210032
Journal: Breast Disease, vol. 41, no. 1, pp. 155-161, 2022
