Invasive breast carcinoma with hyaline globules (“thanatosomes”)

Article type: Case Report

Authors: Bezić, Joško^a;

Affiliations: [a] Institute of Pathology, Forensic Medicine and Cytology, Clinical Hospital Center Split, Split, Croatia

Correspondence: [*] Corresponding author: Joško Bezić, Institute of Pathology, Forensic Medicine and Cytology, Clinical Hospital Center Split, Spinčićeva 1, 21 000 Split, Croatia. Tel.: +385 21 556 512; Fax: +385 21 389 510; E-mail: [email protected]

Abstract: Hyaline globules (thanatosomes) have been observed in many neoplastic and non-neoplastic processes. They represent terminal cytoplasmic structures associated with cytoplasmic blebbing, which are related to cell injury and apoptosis. Thanatosomes are reported rarely in breast tumors. Here we describe a case of invasive breast cancer of no special type with abundant thanatosomes.

Keywords: Breast, breast cancer, apoptosis, thanatosomes

DOI: 10.3233/BD-190414

Journal: Breast Disease, vol. 39, no. 1, pp. 43-45, 2020