Diagnosis and screening of cancer tissues by fiber-optic probe Raman spectroscopy

Article type: Research Article

Authors: Krafft, C.^; | Dochow, S. | Latka, I. | Dietzek, B.^; | Popp, J.^;

Affiliations: Institute of Photonic Technology, Jena, Germany | Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich Schiller University Jena, Jena, Germany

Note: [] Corresponding author: C. Krafft, Institute of Photonic Technology, Albert Einstein Straße 9, D-07745 Jena, Germany. Tel.: +49 3641 206306; Fax: +49 3641 206399; E-mail: [email protected].

Abstract: Raman spectroscopy is an emerging biophotonic tool that advanced in recent years due to steady improvements in instrumentation for excitation and collection, and the availability of fiber optic probes. This review describes the principles of fiber optic Raman probes and their applications in cancer research of lung, breast, skin, bladder, brain, cervix, oral cavity and gastrointestinal tract.

Keywords: Raman spectroscopy, fiber-optic probe, cancer, carcinoma

DOI: 10.3233/BSI-2012-0004

Journal: Biomedical Spectroscopy and Imaging, vol. 1, no. 1, pp. 39-55, 2012