Affiliations: Department of Psychiatry, Charing Cross Hospital, Fulham Palace Road, London W6 8RF, UK | Academic Department of Psychiatry, Charing Cross and Westminster Medical School, St Dunstan's Road, London W6 8RP, UK
Note: [] Correspondence to: B.K. Puri at above address
Abstract: Cranial single-photon emission computerized tomography (SPECT or SPET) can now give regional cerebral blood flow images with a resolution approaching that of positron emission tomography (PET). In this paper, the use of high resolution SPECT neuroimaging in neuropsychiatric disorders, including Alzheimer's disease, multi-infarct dementia, Pick's disease, progressive supranuclear palsy, Korsakoff's psychosis, Creutzfeld-Jakob disease, Parkinson's disease, Huntington's disease, schizophrenia, mood disorders, obsessive–compulsive disorder, HIV infection and AIDS is reviewed. Finally, further potential research and clinical uses, based on ligand studies, are outlined.
Keywords: Ligand studies, Neuroimaging, Neuropsychiatric disorders, PET, SPECT, SPET
