Delusion of pregnancy: A case revisited

Issue title: Includes Special Section: Abstracts from the Joint Meeting of the FESN/GNP, Sept. 12-14, 2013, Berlin, Germany

Article type: Research Article

Authors: Larner, A.J.

Affiliations: Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool, L9 7LJ, United Kingdom. Tel.: +44 151 529 5727; Fax: +44 151 529 8552; E-mail: [email protected]

Abstract: A patient with delusion of pregnancy as an early feature of frontotemporal dementia with motor neurone disease (FTD/MND) who was reported some years ago was posthumously found to harbor the C9ORF72 hexanucleotide repeat expansion, now known to be the most common genetic cause of FTD/MND. Some series have found psychosis to be common in FTD associated with this mutation, so this test should be considered in individuals with clinical features of FTD and MND and/or with a family history of either disorder who present with bizarre delusions.

Keywords: Delusion of pregnancy, frontotemporal dementia with motor neurone disease, C9ORF72 mutation

DOI: 10.3233/BEN-120324

Journal: Behavioural Neurology, vol. 27, no. 3, pp. 293-294, 2013