The processing of global and local visual information in Alzheimer's disease

Article type: Research Article

Authors: Eriko Matsumoto, | Yoshitaka Ohigashi, | Misato Fujimori, | Etsuro Mori,

Affiliations: Department of Graduated school of human and environmental studies, Kyoto University, Japan | Divisions of Clinical Neurosciences and Neuroimaging Research, Hyogo Institute for Aging Brain and Cognitive Disorders, Himeji, Japan

Note: [] Graduated school of human and environmental studies, Kyoto University, 606-8501 Yoshida-honmachi, Sakyo-ku, Kyoto, Japan. Tel.: +81 78 969 2266; Fax: +81 78 969 2200; E-mail: [email protected]

Abstract: We examined the quantitative and qualitative difference of the pattern with visuo-cognitive processing impairment in patients with early onset AD (EOAD) and late onset AD (LOAD). We use a visual attention task introduced by Navon (1977) to examine the function to integrate local visual stimuli into global image. Although the ability to identify solid digits ether of large and small size presented at the same exposure duration, EOAD performance was poor in the global perception especially at the short duration (20~msec). We provide evidence that this dysfunction is attribute to the AD pathology specific to early onset type.

Keywords: visual attention, global and local perception, Alzheimer's disease, age at onset

Journal: Behavioural Neurology, vol. 12, no. 3, pp. 119-125, 2000