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Technology and Health Care is intended to serve as a forum for the presentation of original articles and technical notes, observing rigorous scientific standards. Furthermore, upon invitation, reviews, tutorials, discussion papers and minisymposia are featured.
The following types of contributions and areas are considered:
1. Original articles:
Technology development in medicine: New concepts, procedures and devices associated with the use of technology in medical research and clinical practice are presented to a readership with a widespread background in engineering and/or medicine.
Significance of medical technology and informatics for healthcare: The appropriateness, efficacy and usefulness deriving from the application of engineering methods, devices and informatics in medicine and with respect to public health are discussed.
2. Technical notes:
Short communications on novel technical developments with relevance for clinical medicine.
3. Reviews and tutorials (upon invitation only):
Tutorial and educational articles for persons with a primarily medical background on principles of engineering with particular significance for biomedical applications and vice versa are presented.
4. Minisymposia (upon invitation only):
Under the leadership of a Special Editor, controversial issues relating to healthcare are highlighted and discussed by various authors.
Abstract: The quantitative assessment of velocity fields can help to get a better understanding of complicated flow patterns which are considered to play an important role in atherosclerotic plaque formation. Magnetic resonance imaging offers the possibility of non-invasive visualization and quantification of blood flow in many larger human arteries and veins. However, the assessment of complex blood flow patterns with conventional gradient echo flow sequences sutler from severe image artifacts. In order to overcome these problems, a partial echo signal acquisition technique which strongly reduces such artifacts may be applied. Using this technique, three dimensional velocity fields were measured in a…bifurcation model, in the human carotid bifurcation and in the human aorta, right downstream of the aortic valve.
Keywords: Complex blood flow, magnetic resonance imaging, atherosclerosis
Abstract: Micro-computed tomography (μCT) is an emerging technique for the non-destructive assessment and analysis of the three-dimensional cancellous bone architecture. However, the procedures and applications used to quantify bone structures are not yet standardized. The aim of this study was to provide more insight in the resolution-dependency of microstructural properties of three-dimensional trabecular bone. Ten iliac crest bone biopsies were measured using a newly devised μCT system providing a nominal isotropic resolution of 14 μm. To study the resolution dependency, the measured data were reconstructed on reduced image arrays with reduction factors ranging from 2 to 20. To assess the structural…properties, morphometric parameters were computed based on a truly three-dimensional approach. The results showed a strong resolution dependency of the structural properties and that, if very precise results are needed, only the highest resolution will predict the correct values. Nevertheless, since the properties either decrease or increase monotonously up to a nominal resolution of about 175 μm, the values appear to be restorable using a suitable calibration procedure.
Keywords: Micro-computed tomography (μCT), trabecular bone architecture, quantitative bone morphology, 3D structural analysis, image resolution
Abstract: This paper focuses on a number of methods for the analysis of the relationship between the arterial baroreflex and different components of blood pressure and heart rate variability. Broad-band spectral analysis techniques have allowed us to obtain experimental evidence that the arterial baroreflex exerts its influence not only on fast but also on slow components of blood pressure and heart rate, i.e., on components with periods longer than 60 sec. Focusing on faster changes in blood pressure and heart rate, both time domain and frequency domain techniques have been developed to track the sensitivity of baroreflex heart rate modulation over…time, either in laboratory or in daily life conditions. These approaches have considerably broadened our understanding of the role of baroreflex modulation of the heart and peripheral circulation in a number of pathological and physiological conditions.