Mediterranean Journal of Nutrition and Metabolism - Volume Pre-press, issue Pre-press
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Mediterranean Journal of Nutrition and Metabolism publishes original scientific papers on metabolism, including diabesity and eating disorders; nutrition (epidemiological, basic, clinical and artificial); dietary and nutritional practices and management and their impact on health from prevention to treatment.
The journal hosts the proceedings of relevant congresses and presents shorter notices focused on the original character of the Mediterranean nutritional civilisation. In addition, this journal is intended as a platform for scientific debate and knowledge-sharing among students and clinical practitioners, and between them and the broader scientific community, and finally as a tool for promoting and enhancing scientific cooperation.
Abstract: BACKGROUND & OBJECTIVE: The prevention of malnutrition is an important factor in the survival of critically ill patients with enteral nutrition. The present study aims to assess the nutritional status and its association with some blood-related markers in critically ill patients with enteral nutrition during hospitalization in the intensive care units (ICUs). METHODS: Totally, 110 patients participated in this study from the time of admission to discharge at five ICUs. The patients’ nutritional status was assessed by subjective global assessment (SGA), Acute Physiology and Chronic Health Evaluation and Albumin, Total Iron Binding Capacity (TIBC), Hemoglobin (Hb), Hematocrit (HCT),…Ferritin, and Feas biochemical indices and anthropometric parameters. RESULTS: Malnutrition prevalence increased significantly on the day of discharge (83.6%) compared to the day of admission (41.8%), according to SGA (P < 0.001). Hb, HCT, serum Fe decreased and ferritin, also TIBC were increased during hospitalization in ICU. The malnutrition risk predictors based on the logistic regression were low levels of Hb (OR = 0.6), HCT (OR = 0.9), Fe (OR = 0.9), Albumin (OR = 0.3) and High Ferritin level (OR = 1.006) on the admission day. Anemia of inflammation (AI) was observed during ICU stay. CONCLUSION: This study demonstrated that malnutrition is an increasing phenomenon in the ICU patients and the delay in patient’s enteral feeding had a direct influence in the prevalence of malnutrition on discharge day.
Keywords: Malnutrition, nutritional status, intensive care units, anemia of inflammation
Abstract: BACKGROUND: Probiotic/synbiotic has the important role of in altering intestinal bacteria, reducing inflammation and improvement of intestinal diseases. OBJECTIVE: We aimed to investigate the effect of synbiotic supplementation on matrix metalloproteinase (MMP) enzymes, hs-CRP, quality of life, dietary intake and weight changes in rectal cancer patients undergoing neoadjuvant chemoradiotherapy (CRT). METHODS: In this study, 46 rectal cancer patients were recruited. Patients were allocated to the synbiotic (n = 23) group or placebo groups (n = 23) receiving 2 synbiotic or placebo capsules for six weeks. Anthropometric measurements, quality of life, dietary intakes, and serum levels of MMP-2, MMP-9,…and hs-CRP were compared before and after intervention with the use of statistical tests. RESULTS: The mean energy, carbohydrate, and protein intake of patients increased in the synbiotic group, while in the placebo group, post intervention, significant reduction was noticed in these parameters (P < 0.05). Synbiotic supplementation caused improvement in global health status, symptom scale scores and scores of functional scale. At the end of intervention, the elevation in hs-CRP, MMP-2, and MMP-9 levels in the placebo group was approximately two and four times higher than the synbiotic group respectively. CONCLUSION: According to our results, synbiotic supplementation may be helpful in cancer patients undergoing CRT. However, further studies must consider synbiotic as a new complementary treatment.
Keywords: Rectal cancer, synbiotic supplementation, preoperative chemoradiotherapy, dietary intake, quality of life.
Abstract: BACKGROUND: Prevention of childhood obesity is recommended throughout interventions aiming at enhancing healthy dietary habits (DH) and increasing physical activity (PA). OBJECTIVE: This cross sectional study aimed at investigating DH and PA, in a sample of Italian children/adolescents. METHODS: We evaluated DH and PA by means of a previously validated questionnaire in 178 children/adolescents (88F/90M, 11.8±2.6 years): 49 normal weight (NW), 76 overweight (OW) and 53 with obesity (OB). Abdominal obesity was defined as Waist to Height Ratio (WHeR) >0.5. RESULTS: DH did not differ in NW subjects compared to OW and OB but…higher PA score (p = 0.001) was observed in NW than OW and OB. No association was found between DH and WHeR, unlike PA. Four clusters of subjects were identified that could be defined by DH and PA; only one cluster, defined by PA, showed a significantly lower WHeR within subjects playing sports at least 3–4 hours/week. Moreover, subjects belonging to this cluster did not skip the main meals, eat a varied diet and drank milk at breakfast. CONCLUSIONS: In our sample PA performed at least 3–4 hours/week is inversely associated with abdominal fat deposition and is expected to positively impact health, protecting from abdominal obesity.