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Biorheology is an international interdisciplinary journal that publishes research on the deformation and flow properties of biological systems or materials. It is the aim of the editors and publishers of
Biorheology to bring together contributions from those working in various fields of biorheological research from all over the world. A diverse editorial board with broad international representation provides guidance and expertise in wide-ranging applications of rheological methods to biological systems and materials.
The aim of biorheological research is to determine and characterize the dynamics of physiological processes at all levels of organization. Manuscripts should report original theoretical and/or experimental research promoting the scientific and technological advances in a broad field that ranges from the rheology of macromolecules and macromolecular arrays to cell, tissue and organ rheology. In all these areas, the interrelationships of rheological properties of the systems or materials investigated and their structural and functional aspects are stressed.
The scope of papers solicited by
Biorheology extends to systems at different levels of organization that have never been studied before, or, if studied previously, have either never been analyzed in terms of their rheological properties or have not been studied from the point of view of the rheological matching between their structural and functional properties. This biorheological approach applies in particular to molecular studies where changes of physical properties and conformation are investigated without reference to how the process actually takes place, how the forces generated are matched to the properties of the structures and environment concerned, proper time scales, or what structures or strength of structures are required.
Biorheology invites papers in which such 'molecular biorheological' aspects, whether in animal or plant systems, are examined and discussed. While we emphasize the biorheology of physiological function in organs and systems, the biorheology of disease is of equal interest. Biorheological analyses of pathological processes and their clinical implications are encouraged, including basic clinical research on hemodynamics and hemorheology.
In keeping with the rapidly developing fields of mechanobiology and regenerative medicine,
Biorheology aims to include studies of the rheological aspects of these fields by focusing on the dynamics of mechanical stress formation and the response of biological materials at the molecular and cellular level resulting from fluid-solid interactions. With increasing focus on new applications of nanotechnology to biological systems, rheological studies of the behavior of biological materials in therapeutic or diagnostic medical devices operating at the micro and nano scales are most welcome.
Abstract: The laminar flow in a rigid tube of a fluid system composed of very thin, coaxial shells of distinct viscous fluids is studied theoretically. The study waives the usual boundary condition of fluid dynamics of zero slip at the boundary. Rather, a finite slip at the wall is allowed and retained in the discussions as a flow parameter, by hypothesis a function of shear stress at the wall, the fluid in contact and the nature of the surface. Slips are also allowed at all fluid interfaces, but assumed negligible as a first approximation after general flow relations are developed. Slip…at the wall is assumed small in comparison with flow velocity to simplify computations. As an application to blood, a two phase particular case of the general fluid system, formed by plasma and red cells in alternate shells, is studied for the following properties: velocity distribution, discharge rate, “apparent” viscosity, dependence of the latter on tube radius, pressure rate and hematocrit. These properties are found to be in agreement with known experimental facts about blood flow. The two phase system exhibits a migration of the red cells toward the tube axis for the small slip-to-velocity ratios considered; the system again parallels blood in its generally acknowledged phenomenon of “axial drift”. Slip appears as a significant element in the interpretation of certain properties of blood flow.
vol. 4, no. 4, pp. 133-150, 1967
Abstract: A theory is presented for determining all of the parameters required to describe the elastic behavior of blood vessels under any static loading. Selected specimens of fresh excised human and canine arteries have been tested in the laboratory and their elastic behavior determined by the theory presented. The results indicate that, for all specimens tested, the arterial wall behaves as a nonlinear, homogeneous, anisotropic,1 1 An anisotropic material is one whose elastic constants are directionally dependent; that is, it is one which possesses a different modulus of elasticity, Poisson’s ratio, and shear modulus along each of the three…orthogonal axes. compressible material and can be described by six elastic constants for each level of strain. Both the circumferential and the axial stiffness are found to increase with internal pressure, and both approach the value for the collagenous fibres at very high internal pressure and axial weight, respectively. The radial stiffness is the smallest of the three and is found to be essentially independent of either internal pressure or axial loading. An anisotropic material is one whose elastic constants are directionally dependent; that is, it is one which possesses a different modulus of elasticity, Poisson’s ratio, and shear modulus along each of the three orthogonal axes.
vol. 4, no. 4, pp. 151-168, 1967
Abstract: A cone and plate viscometer is described, together with notes on the calibration, linearity and general performance of this instrument with Newtonian fluids and blood. The influence of edge effects is minimised by the use of a guard ring, and automatic recording of shear stress obtained at a continuous range of shear rates from 0.1 to 40 sec−1 is possible.
vol. 4, no. 4, pp. 169-174, 1967
Abstract: Blood flow in tapered tubes may be analyzed by considering a tapered tube to consist of segments of straight tubes. This has been shown to result in the same equation as that developed by Bond [Phil. Mag. 50 , 1058, 1925], for uniform tapered tubes. When flow is toward the converging section, theoretical and experimental results are in close agreement. In tubes of relatively large diameter where the influence of a marginal gap is negligible, experimental values agree well with the anticipated values. Under conditions where the influence of a marginal gap becomes important in cylindrical tubes,…the calculated and anticipated values diverge unless the probable gap width based on formulae validated in straight tubes are considered in the calculation. This strongly suggests that marginal layers develop in tapered tubes similar to those in straight tubes.
vol. 4, no. 4, pp. 175-183, 1967
Abstract: The mechanical properties of raw skins of sheep and goat and hides of cow and buffalo and their constituent fibres obtained from different sites were investigated. The locations chosen were neck, shoulder, front shank, belly, butt, official butt, tail end and back shank and the properties investigated were apparent density, tensile strength and elongation at break. The apparent density was the highest in the shoulder region followed by butt, belly, front shank, back shank, neck, leg, tail end and knee regions. The tensile strength was the highest in the belly, shoulder, butt, front shank, back shank, leg, neck, tail end…and knee regions. The order from the highest to the lowest in the elongation at break was belly, back shank, front shank, butt, neck, knee, leg, shoulder and tail end. The same trend was observed in all the hides and skins studied. There was no appreciable difference between the mean breaking length of fibres obtained from various locations.
vol. 4, no. 4, pp. 185-191, 1967