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A three-dimensional model and numerical simulation regarding thermoseed mediated magnetic induction therapy conformal hyperthermia

Issue title: Papers from the 4th International Conference on Biomedical Engineering and Biotechnology (ICBEB2015), 18-21 August 2015, Shanghai, China ``New Paradigms for Biomedical Engineering and Biotechnology''

Article type: Research Article

Authors: Wang, Heng | Wu, Jianan | Zhuo, Zihan | Tang, Jintian*

Affiliations: Key Laboratory of Particle Technology and Radiation Imaging of Ministry of Education, Department of Engineering Physics, Tsinghua University, Beijing, China

Correspondence: [*] Corresponding author: Jintian Tang, Key Laboratory of Particle Technology and Radiation Imaging of Ministry of Education, Department of Engineering Physics, Tsinghua University, Beijing 100084, China. Tel.: +86 010 62796769; Fax: +86 010 62789237; E-mail:[email protected]

Keywords: Magnetic induction hyperthermia, numerical simulation, tissue thermal damage, FVM

DOI: 10.3233/THC-161211

Journal: Technology and Health Care, vol. 24, no. s2, pp. S827-S839, 2016

Published: 13 June 2016
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Abstract

In order to ensure the safety and effectiveness of magnetic induction hyperthermia in clinical applications, numerical simulations on the temperature distributions and extent of thermal damage to the targeted regions must be conducted in the preoperative treatment planning system. In this paper, three models, including a thermoseed thermogenesis model, tissue heat transfer model, and tissue thermal damage model, were established based on the four-dimensional energy field, temperature field, and thermal damage field distributions exhibited during hyperthermia. In addition, a numerical simulation study was conducted using the Finite Volume Method (FVM), and the accuracy and reliability of the magnetic induction hyperthermia model and its numerical calculations were verified using computer simulations and experimental results. Thus, this study promoted the application of computing methods to magnetic induction therapy and conformal hyperthermia, and improved the accuracy of the temperature field and tissue thermal damage distribution predictions.

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