Effect of elasticity on wall shear stress inside cerebral aneurysm at anterior cerebral artery

Article type: Research Article

Authors: Xu, Lijian^a | Sugawara, Michiko^a | Tanaka, Gaku^a | Ohta, Makoto^b | Liu, Hao^c | Yamaguchi, Ryuhei^{c; *}

Affiliations: [a] Graduate School of Engineering, Chiba University, Chiba, Japan | [b] Institute of Fluid Science, Tohoku University, Miyagi, Japan | [c] Graduate School of Engineering, Chiba University, Chiba, Japan

Correspondence: [*] Corresponding author: Ryuhei Yamaguchi, Graduate School of Engineering, Chiba University 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, Japan. Tel.: +81 43 251 1111 ext.4538; Fax: +81 43 290 3335; E-mail:[email protected]

Abstract: BACKGROUND: Many numerical studies have been published with respect to about flow structures around cerebral aneurysm assuming to be rigid. Furthermore, there is little experimental research concerning aneurysm with elastic wall. Wall shear stress in elastic wall comparing with rigid wall should be clarified in experimental approach and verified in CFD. OBJECTIVE: We have experimentally realized elastic aneurysm model accompanying with wall deformation. Wall shear stress was examined for both rigid and elastic aneurysm models in pulsatile flow. METHODS: Effect of elasticity on wall shear stress inside aneurysm induced at the apex of anterior cerebral artery was experimentally examined by particle image velocimetry in vitro. In order to adjust the wall deformation, the pressure adjustment chamber was specially equipped outside the aneurysm wall. RESULTS: Effect of elasticity on wall shear stress was noticed on the comparison with that of rigidity. Wall elasticity reduced the peak magnitude, the spatial and temporal averaged wall shear stress comparing with those of wall rigidity experimentally. These reductions were endorsed by fluid-structure interaction simulation. CONCLUSION: Elastic wall comparing with rigid wall would reduce the peak magnitude, the spatial and temporal averaged wall shear stress acting on vascular wall.

Keywords: Cerebral aneurysm, elasticity, wall shear stress, PIV, CFD, hemodynamics

DOI: 10.3233/THC-161135

Journal: Technology and Health Care, vol. 24, no. 3, pp. 349-357, 2016