Searching for just a few words should be enough to get started. If you need to make more complex queries, use the tips below to guide you.
Article type: Research Article
Authors: Horiuchi, Tetsuyaa; b; * | Yamamoto, Shujic | Murase, Kenyaa
Affiliations: [a] Department of Medical Physics and Engineering, Division of Medical Technology and Science, Course of Health Science, Graduate School of Medicine, Osaka University, Osaka, Japan | [b] Department of Radiology, National Center for Child Health and Development, Tokyo, Japan | [c] LISIT Co. Ltd, Tokyo, Japan
Correspondence: [*] Corresponding author: Tetsuya Horiuchi, Department of Medical Physics and Engineering, Division of Medical Technology and Science, Course of Health Science, Graduate School of Medicine, Osaka University, 1-7 Yamadaoka, Suita, Osaka 565-0871, Japan. Tel.: +81 6 6879 2571; Fax: +81 6 6879 2571; E-mail: [email protected].
Abstract: Background:Projection-data based method is established as an accurate simulation of low-dose CT, but cooperation of the CT manufacturer is required. Image-based method is awaited for independent and efficient research. Objective:To develop and verify image-based method for adding noise to DICOM images. Methods:This technique reproduces projection data by fan-beam transform of the DICOM image data and by creating and reconstructing noise projections into a noise image that can be added to the original image. A cylindrical test phantom and anthropomorphic phantom were used to verify the simulation method for both standard and adaptive iterative reconstruction methods. Results:The simulated images compared favorably with actual images. Standard deviation difference of the simulated images were 1.27% ± 0.81% (cylindrical phantom) and ranged from 1.61% ± 0.81% (head), to 5.41% ± 1.57% (hepatic portal region) (anthropomorphic phantom). The standard deviation difference of the cylindrical phantom with the adaptive iterative technique were 3.41% ± 1.76% at 50% ASIR and 3.85% ± 1.82% at 100% ASIR. The simulated noise power spectra of both types of images were comparable to the actual images. Conclusion:We developed and validated a DICOM image-based low-dose simulation that allows researchers to perform dose reduction research independently and efficiently.
Keywords: Computed tomography, CT, noise, dose reduction, computer simulation
DOI: 10.3233/THC-130746
Journal: Technology and Health Care, vol. 21, no. 5, pp. 441-454, 2013
IOS Press, Inc.
6751 Tepper Drive
Clifton, VA 20124
USA
Tel: +1 703 830 6300
Fax: +1 703 830 2300
[email protected]
For editorial issues, like the status of your submitted paper or proposals, write to [email protected]
IOS Press
Nieuwe Hemweg 6B
1013 BG Amsterdam
The Netherlands
Tel: +31 20 688 3355
Fax: +31 20 687 0091
[email protected]
For editorial issues, permissions, book requests, submissions and proceedings, contact the Amsterdam office [email protected]
Inspirees International (China Office)
Ciyunsi Beili 207(CapitaLand), Bld 1, 7-901
100025, Beijing
China
Free service line: 400 661 8717
Fax: +86 10 8446 7947
[email protected]
For editorial issues, like the status of your submitted paper or proposals, write to [email protected]
如果您在出版方面需要帮助或有任何建, 件至: [email protected]