Affiliations: [a] Department of Nutrition and Public Health, Faculty of Medicine, Universitas Katolik Indonesia Atmajaya, North Jakarta, Indonesia
| [b] Department of Nutrition, Faculty of Medicine, Universitas Indonesia, Central Jakarta, Indonesia
| [c] Division of Endocrine and Matabolic, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Central Jakarta, Indonesia
| [d] Division of Gastroenterohepatology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Central Jakarta, Indonesia
| [e] Department of Biology, Faculty of Medicine, Universitas Katolik Indonesia Atmajaya, North Jakarta, Indonesia
Correspondence:
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Corresponding author: Nanny Djaja, Department of Nutrition and Public Health, Faculty of Medicine, Universitas Katolik Indonesia Atmajaya, Pluit Raya Street No. 2, North Jakarta, Indonesia. Tel.: +62 021 6603168; Fax: +62 021 6606123; E-mail: [email protected].
Abstract: BACKGROUND:Involving natural food ingredients in controlling blood glucose in diabetic patients has been widely studied. However, there is little information about the effect of the ingredients on improvement of clinical, laboratory, and gut function markers. OBJECTIVE:This study was aimed to examine the effect of Job’s tears-enriched yoghurt on weight, fasting blood glucose, GLP-1, and Calprotectin in patients with type 2 Diabetes Mellitus. METHODS:Sixty male and female subjects with T2DM participating in this study were divided in two groups; received yoghurt (control group/C) and Job’s tears-enriched yoghurt (treatment group/T). Subjects use metformin only were allowed. Job’s tears seed was extracted using a standard process. Height and weight were measured. Laboratory examination for fasting blood glucose, GLP-1, and calprotectin were performed using standard methods. Appropiate statistical analysis tests were applied to examine variables change within and between groups. Significancy was set at p <0.05.
