Cardiovascular Research center, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran
Biochemistry of Nutrition Research Center, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran
Department of Statistics, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran
Brighton & Sussex Medical School, Division of Medical Education, Mayfield House, University of Brighton, UK
Institute of Genetics and Developmental Biology, International College, University of Chinese Academy of Science (IC-UCAS), Beijing, China
| [f] Key State Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Chaoyang, Beijing, China
Corresponding author: Majid Ghayour-Mobarhan, MD, MSc, PhD, Biochemistry of Nutrition Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. Tel.: +989155171478; Fax: +985117112596; firstname.lastname@example.org
Abstract: OBJECTIVE: Hypertension (HTN) is an important risk factor for cardiovascular disease (CVD) affecting more than a quarter of the world’s adult population. The aim of this survey was to determine the prevalence of HTN, pre-HTN, and awareness of HTN in an Iranian population, and to assess the factors associated with HTN and pre-HTN. MATERIALS AND METHODS: The MASHAD study started in 2010 and will continue until 2020. The demographic, anthropometric and lifestyle data were collected by two certified health care professionals and a nurse. SPSS software was used for statistical analysis RESULTS: There were a total of 9762 participants, of whom 40 % were males (n = 3903) and 60 % females (n = 5859). The means (and SD) age of the population samples were 48.8±8.4 years for the male and 47.6±8.0 years for the female subgroups. 12% (95% CI, 11.5% –12.6%) were classified as pre-hypertensive, 23% (95% CI, 22.2% –23.9%) as hypertensive and 65 % were normotensive. Of the group that was hypertensive, 55% were individuals with previously undetected HTN. The prevalence of undetected HTN in the sub-group with diabetes mellitus (DM) was 42%; and in those who were current smoking the prevalence of undetected HTN was 54.9%, indicating a high degree of co-clustering of cardiovascular risk factors. CONCLUSION: In an unselected population from North-Eastern Iran, hypertension was common, often undetected and frequently co-existed with other CVD risk factors.