Phytochemical analysis of Calotropis procera with antimicrobial activity investigation

Article type: Research Article

Authors: Morsy, Nagy^{a; b; c; *} | Al Sherif, Emad A.^{d; e; f} | Abdel-rassol, Tayseer M.A.^{d; g}

Affiliations: [a] Department of Chemistry, Faculty of Sciences and Arts, Khulais, King Abdulaziz University, Kingdom of Saudi Arabia | [b] Department of Chemistry, Faculty of Sciences and Arts, Khulais, University of Jeddah, Kingdom of Saudi Arabia | [c] Department of Chemistry of Natural Compounds, National Research Centre, Dokki, Cairo, Egypt | [d] Department of Biology, Faculty of Sciences and Arts, Khulais, King Abdulaziz University, Kingdom of Saudi Arabia | [e] Department of Biology, Faculty of Sciences and Arts, Khulais, University of Jeddah, Kingdom of Saudi Arabia | [f] Department of Botany, Faculty of Science, BeniSuef University, BeniSuef, Egypt | [g] Department of Botany & Microbiology, Faculty of Science, Suez Canal University, Egypt

Correspondence: [*] Corresponding author: Nagy Morsy, Tel.: +966565545117; Fax: +96626952000 26084; E-mail: [email protected].

Abstract: Phytochemical and biological activity screening are the primary steps for isolation of new biologically active compounds, which lead to the discovery of new drugs. Calotropis procera (Ait). R. Br. (Asclepiadaceae) are widely used in traditional medicine to treat various diseases. To provide a scientific basis for traditional uses of Calotropis procera, the crude methanol extract of plant organs were investigated phytochemically. The plant contains various classes of bioactive secondary metabolites such as terpenoids, flavonoids, saponins, steroids and cardiac glycosides. The antimicrobial activities of the crude extracts of various plant organs were investigated too. The results were sufficiently positive to encourage further investigation.

Keywords: Phytochemical analysis, antimicrobial investigations, Calotropis procera

DOI: 10.3233/MGC-160206

Journal: Main Group Chemistry, vol. 15, no. 3, pp. 267-273, 2016