Color-map virtual touch tissue imaging (CMV) combined with BI-RADS for the diagnosis of breast lesions

Article type: Research Article

Authors: Lian, Kai-Mei | Lin, Teng^{; *}

Affiliations: Department of Ultrasound, The First Affiliated Hospital of Shantou University Medical College, Shantou City, Guangdong Province, China

Correspondence: [*] Correspondence to: Teng Lin, Department of Ultrasound, The First Affiliated Hospital of Shantou University Medical College, Shantou City, Guangdong Province, P.R. China. Tel.: 86-075488258290; [email protected]; ORCID ID: 0000-0003-3244-0329

Abstract: OBJECTIVE:To investigate the importance of color-map virtual touch tissue imaging (CMV) in assisting Breast Imaging Reporting and Data Systems (BI-RADS) in diagnosing malignant breast lesions. METHODS:A dataset included 134 patients and 146 breast lesions was assembled. All patients underwent biopsy or surgical excision of breast lesions, and pathological results were obtained. All patients with breast lesions also underwent conventional ultrasound (US) and CMV. Each lesion was assigned a CMV score based on the color pattern of the lesion and surrounding breast tissue and a BI-RADS classification rating based on US characteristics. We compared the diagnostic performance of using BI-RADS and CMV separately and their combination. RESULTS:BI-RADS (odds ratio [OR]: 3.665; 95% confidence interval [CI]: 2.147, 6.258) and CMV (OR: 6.616; 95% CI: 2.272, 19.270) were independent predictors of breast malignancy (all P < 0.05). The area under the receiver operating characteristic curves (AUC) for either CMV or BI-RADS alone was inferior to that of the combination (0.877 vs. 0.962; 0.938 vs. 0.962; all P < 0.05). CONCLUSIONS:The performance of BI-RADS in diagnosing breast lesions is significantly improved by combining CMV. Therefore, we recommend CMV as an adjunct to BI-RADS.

Keywords: Ultrasound, virtual tissue imaging, BI-RADS, regression analysis

DOI: 10.3233/XST-211110

Journal: Journal of X-Ray Science and Technology, vol. 30, no. 3, pp. 447-457, 2022