Affiliations: Department of Urology, the Second Affiliated Hospital
of Soochow University, Suzhou, Jiangsu, China | Wake Forest School of Medicine, Wake Forest Institute
for Regenerative Medicine, Winston-Salem, NC, USA
Note: [] Corresponding author: Wei Tao, Department of Urology, the Second
Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China. Tel.: +86
013 382 503 391; E-mail: [email protected]
Abstract: OBJECTIVE: We evaluated the safety and efficacy of 120W
potassium-titanyl-phosphate (KTP) laser vaporization on patients with
non-muscle invasive bladder cancer compared with standard transurethral
resection of bladder tumor (TUR-BT). MATERIALS AND METHODS: One
hundred and fifty-eight patients of non-muscle invasive bladder cancer who
underwent either 120W potassium-titanyl-phosphate (KTP) laser vaporization
(HPS group, n=74) or transurethral resection of the bladder tumor (TUR-BT
group, n=84) were analyzed respectively. The preoperative, intraoperative
and postoperative clinical data were recorded and compared in two groups. RESULTS: All patients were successfully treated with 120W-KTP laser
vaporization or TUR-BT. No significant differences were observed in operative
time, perioperative and postoperative serum sodium and hemoglobin levels
between two groups. Importantly, HPS had less specific side effects of TURBT,
such as obturator nerve reflex, postoperative bladder irrigation and
catheterization time, which shows statistic difference significantly (p<
0.05). Recurrence rate was lower in HPS group than those in TUR-BT group. CONCLUSION: The 120W-HPS KTP laser as a safe and feasible procedure
provids an alternative for the patients with non-muscle invasive bladder
cancer, especially for those on anticoagulation therapy.
Keywords: Bladder cancer, transurethral resection, laser surgery
