GreenLight HPS 120-W laser vaporization versus transurethral
resection of the prostate for treatment of benign prostatic hyperplasia: A
prospective randomized trial
Issue title: Recent Advances in Clinical Diagnosis and
Therapeutics
Affiliations: Department of Urology, the Second Affiliated Hospital
of Soochow University, Suzhou, Jiangsu, China | Wake Forest Institute for Regenerative Medicine, Wake
Forest School of Medicine Medical Center Blvd, Winston-Salem, NC, USA
Note: [] Corresponding author: Yuxi Shan, Department of Urology, the
Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China. Tel.:
+86 189 1315 8526; E-mail: [email protected]
Abstract: The most recent advance in laser treatment of benign prostatic
hyperplasia (BPH) is the introduction of a high-performance system (HPS) 120-W
laser. The HPS laser beam at a wavelength of 532~nm is highly absorbed by
oxyhemoglobin in the tissue and maintains focus with negligible divergence up
to 3 mm from the fiber and with limited divergence at 5 mm. This study is
designed to evaluate the three-year clinical efficacy and safety of
photoselective vaporization of the prostate (PVP, n=100 cases) with GreenLight
HPS laser compared with transurethral resection of the prostate (TURP, n=100
cases) for treatment of BPH. The results showed that the mean operating time,
catheterization time and admission time were significantly shorter in the PVP
group, respectively. There were dramatic improvements in International Prostate
Symptom Score (IPSS), quality of life (Qol), maximum flow rate (Qmax) and
postvoid residual (PVR) compared with preoperative values and the degree of
improvements was comparable in both groups. The intraoperative complications
were lower in PVP group. In summary, PVP is an effective technique in patients
with BPH, when compared to TURP, producing equivalent improvements in IPSS,
Qmax, Qol and PVR with the advantages of markedly reduced catheterization time,
admission time and adverse events.
Keywords: Benign prostatic hyperplasia, laser therapy, GreenLight HPS laser, transurethral resection of the prostate
