Affiliations: [a] Physical Medicine and Rehabilitation Department, Dr. Lutfu Kirdar Kartal Training Hospital, Istanbul, Turkey | [b] Physical Medicine and Rehabilitation, Children's Hospital Colorado, Aurora, CO, USA
Corresponding author: Ozge Kenis-Coskun, Dr. Lutfi Kirdar Kartal Training Hospital, Physical Medicine and Rehabilitation Department, Şmsi Denizer Cad. E-5 Karayolu Cevizli Mevkii 34890 Istanbul, Turkey. Tel.: +90 5058294947; E-mail:[email protected]
Abstract: Charcot Marie Tooth (CMT) disease is the most common hereditary sensorimotor neuropathy that has a slow onset. It presents usually in childhood, starting distally and from the lower limbs progressing to more proximal muscles. Due to the lack of curative medical treatments and the problematic outcomes of surgical intervention, rehabilitation continues to play a major role in treatment. This paper aims to summarize the rehabilitation approaches like aerobic, stretching and strengthening exercises. Orthotics is another important part of treatment that complete rehabilitative approaches. Orthotic devices that are currently being used and investigated in patients with CMT are also reviewed. The evidence shows that exercise is effective in improving strength and general fitness. Stretching is somewhat effective in maintaining range of motion. Orthotic devices are the mainstay of maintaining mobility and ambulation and upper extremity function.