Affiliations: [a]
Children’s Hospital Colorado, Aurora, CO, USA
| [b]
Columbia University Irving Medical Center, NewYork-Presbyterian Hospital, New York, NY, USA
| [c]
University of Texas Southwestern Medical Center, Dallas, TX, USA
Correspondence:
[*]
Corresponding author: Jeremy Roberts, MD, Children’s Hospital Colorado, 13123 E 16th Ave., Box 285, Aurora, CO 80045, USA. Tel.: +1 5164568310; E-mail: [email protected]; [email protected].
Abstract: This report describes a 15-year-old female with known spastic and dystonic quadriplegic cerebral palsy (CP), Gross Motor Function Classification System IV, and obstructive sleep apnea (OSA). She experienced decreased apneic episodes after receiving onabotulinumtoxin A (BoNT-A) injections for the treatment of oromandibular dystonia (OMD). After her OSA diagnosis, she initially received injections to the bilateral masseter and temporalis muscles with no effect on the frequency of nightly apneic episodes. Subsequently, the bilateral lateral pterygoid muscles were added and she was later noted to have fewer apneic episodes overnight. This case report describes the use of BoNT-A in the muscles of mastication for management of OMD and the ensuing improvement in OSA in a teenager with CP.
Keywords: Oromandibular dystonia, botulinum toxin, apnea, cerebral palsy, case report