Affiliations: Department of Endocrinology, UCSF Benioff Children's
Hospital Oakland, 757 52nd Street, Oakland, CA 94609, USA. Tel.: +1 510 428
3654; Fax: +1 510 450 5614; E-mail: JeOlson@mail.cho.org
Abstract: Bisphosphonates are being used more frequently as part of the
multi-disciplinary management of moderate to severe Osteogenesis Imperfecta
(OI). This report details the development of respiratory failure during the
second infusion of pamidronate in a 3.5 year-old male with osteogenesis
imperfecta type 1 and no prior history of respiratory disease.