Respiratory failure during infusion of pamidronate in a 3 year-old male with osteogenesis imperfecta: A case report

Issue title: Bone Health in Children with Special Health Care Needs

Article type: Research Article

Authors: Olson, Jennifer Ann

Affiliations: Department of Endocrinology, UCSF Benioff Children's Hospital Oakland, 757 52nd Street, Oakland, CA 94609, USA. Tel.: +1 510 428 3654; Fax: +1 510 450 5614; E-mail: [email protected]

Abstract: Bisphosphonates are being used more frequently as part of the multi-disciplinary management of moderate to severe Osteogenesis Imperfecta (OI). This report details the development of respiratory failure during the second infusion of pamidronate in a 3.5 year-old male with osteogenesis imperfecta type 1 and no prior history of respiratory disease.

Keywords: Osteogenesis imperfecta, bisphosphonates, pamidronate, respiratory distress, respiratory failure

DOI: 10.3233/PRM-140284

Journal: Journal of Pediatric Rehabilitation Medicine, vol. 7, no. 2, pp. 155-158, 2014