Moyamoya disease presenting with ischemic stroke in association with diabetic ketoacidosis

Article type: Research Article

Authors: Habib, Hamed S.

Affiliations: Department of Pediatrics, Faculty of Medicine, King Abdelaziz University, Jeddah, Saudi Arabia

Note: [] Correspondence: Hamed S. Habib, Associate Professor Pediatric Department, Faculty of Medicine, King Abdelaziz University, Jeddah, Saudi Arabia. Tel.: +966 544680681; E-mail: taher2001@ hotmail.com

Abstract: Moyamoya disease is a progressive vascular disease associated with steno-occlusion of the terminal portions of the internal carotid arteries and with several congenital and acquired conditions, including ischemic stroke in young children. This case report describes the discovery of an unusual association between moyamoya disease and type 1 diabetes mellitus in a 9-year-old child presenting with stroke-associated diabetic ketoacidosis. Discovery of this case highlights the importance of considering stroke as well as cerebral edema, the more likely etiology, in the differential diagnosis of neurological deterioration in children with diabetic ketoacidosis, as well as considering moyamoya syndrome in the diagnosis of diabetic children presenting with stroke.

Keywords: Cerebral edema, diabetes mellitus, ischemia, ketoacidosis, moyamoya disease, stroke

DOI: 10.3233/JPN-120589

Journal: Journal of Pediatric Neurology, vol. 11, no. 1, pp. 39-42, 2013