Affiliations: Florida State University College of Medicine,
Tallahassee, FL, USA | Department of Human Genetics, Emory University School
of Medicine, Atlanta, GA, USA | Department of Neurosurgery, Emory University School of
Medicine, Atlanta, GA, USA
Note: [] Correspondence: Dr. Jeannie Visootsak, %Assistant Professor,
Emory University School of Medicine, 2165 N. Decatur Rd, 30030, Decatur, GA,
USA. Tel.: +1 404 778 8590; E-mail: [email protected]
Abstract: Dandy-Walker syndrome (DWS), or Dandy-Walker complex, is a
congenital brain malformation of the posterior fossa, typically resulting in
developmental delay and cognitive disability. The co-occurrence of Down
syndrome (DS) and DWS is relatively uncommon; thus, its impact on developmental
outcomes has not been fully elucidated. Herein, we report a case of a
37-month-old child with DS and DWS, who is functioning at the following
age-equivalent: gross motor at a 9-mo level, fine motor 6 mo, expressive
language 14 mo, receptive language 9 mo. As such, it is important to determine
how the DWS influences developmental outcomes, and appreciate the importance of
early interventional therapy.
Keywords: Down syndrome, Dandy-Walker syndrome, developmental outcomes
