Locked-in syndrome in a child with tubercular meningitis

Article type: Research Article

Authors: Rana, Kamer S. | Chauhan, Lokesh | Sharma, Mukti | Kumar, Yogesh | Singh, Giriraj

Affiliations: Department of Pediatrics, Army Hospital (Research & Referral), Delhi, India

Note: [] Correspondence: Dr. Kamer S. Rana, Department of Pediatrics, Army Hospital (Research & Referral), Delhi Cantt, New Delhi, India. Tel.: +91 (0) 9910056737; E-mail: [email protected]

Abstract: Locked-in syndrome (LIS) is one of the ventral pontine syndromes and is rare in childhood. The commonest cause in adults is basilar artery stroke. Central nervous system tuberculosis causing LIS is extremely rare. We present a case of a 7-year-old boy who presented with classical LIS due to tubercular meningitis with magnetic resonance imaging findings suggestive of demyelination in the midbrain, cerebral peduncles and posterior superior pons bilaterally. Over the following months, he showed remarkable recovery and was able to walk without assistance, feed himself, and speak.

Keywords: Locked-in syndrome, tubercular meningitis

DOI: 10.3233/JPN-2011-0491

Journal: Journal of Pediatric Neurology, vol. 9, no. 3, pp. 365-368, 2011