Affiliations: Department of Neonatology, University Hospital of
Wales, Cardiff, UK | Department of Pediatrics, Washington University, St
Louis, MO, USA
Note:  Correspondence: Dr. Divyen K. Shah, Department of Neonatology,
University Hospital of Wales, Heath Park, Cardiff CF14 4XW, UK. Tel.: +44 29
2074 2432; Fax: +44 29 2074 4719; E-mail: [email protected]
Abstract: Electrographic seizures are an important manifestation of cerebral
pathology in the newborn. Over the last few decades, automated seizure
detection systems have been devised in order to assist the clinician's review.
Basic principles and approaches of systems applied to the newborn, using
multiple channels are compared. The application of a system using two channels
of electroencephalography with amplitude-integrated electroencephalography
monitoring in the newborn is also described. Newer and novel approaches to
automated seizure detection are also discussed.