Affiliations: Department of Pediatrics, Advanced Pediatric Centre,
Postgraduate Institute of Medical Education and Research, India | Department of Radiodiagnosis, Advanced Pediatric
Centre, Postgraduate Institute of Medical Education and Research, India
Note:  Correspondence: Munni Ray, M.D., Department of Neuropsychiatry
for Children and Adolescents at AKH, Vienna, Austria. Department of Pediatrics,
PGIMER, Chandigarh, 160012, India. E-mail: [email protected],
Abstract: Acute bilateral striatal necrosis is considered to be a rare
heterogeneous entity, in view of the variability of its clinical presentation.
We report a 4-year-old girl presented with typical clinical features of measles
associated with acute bilateral striatal necrosis. The clinical symptoms were
an abrupt onset of seizures, hemiplegia, expressive aphasia and extrapyramidal
signs on the seventh day of illness. Serum was positive for measles IgG and
IgM. Cranial magnetic resonance imaging showed hyperintensities on T2 weighted
images affecting the putamen and caudate nuclei bilaterally. Neurologic
recovery occurred within six weeks following therapy with corticosteroids.
Repeated magnetic resonance imaging in follow up showed significant resolution
of the lesions.