Affiliations: Department of Pediatrics, Section of Critical Care, Indiana University School of Medicine, Indianapolis, IN, USA | Department of Pediatrics, Division of Critical Care Medicine, Medical College of Wisconsin, Milwaukee, WI, USA
Note:  Corresponding author: Dr. Jennifer McArthur, Medical College of Wisconsin, Department of Pediatrics, Division of Critical Care Medicine MS #681, 9000 West Wisconsin St., Milwaukee, WI 53226, USA. Tel.: +1 414 266 3360; Fax: +1 414 266 3563; E-mail: [email protected]
Abstract: Noninfectious pulmonary complications of hematopoietic stem cell transplant are currently more prevalent than infectious complications. Unfortunately, the pathophysiology basis is not completely understood. However, there is a string association with graft-versus-host disease for many of them. Therefore, an important component of their pathophysiology is likely an allo-immune response. There is much research that needs to be conducted to improve the less than optimal outcomes for these disorders.
Keywords: Hematopoietic cell transplant, pulmonary complications, graft versus host disease