Affiliations: Department of Pediatrics, Division of Neonatology,
Institute of Medical Sciences, Banaras Hindu University, Varanasi, India
Note:  Correspondence: Dr. Sriparna Basu, Department of Pediatrics,
Institute of Medical Sciences, Banaras Hindu University, Varanasi –
221005, India. Tel.: +91 9935340260; Fax: +91 54322367568; E-mail:
Abstract: Cytomegalovirus (CMV) is one of the most common congenital viral
infections in humans. It can follow both primary and recurrent maternal
infections and is an important cause of morbidity and mortality in newborns.
The effects of congenital CMV infection vary widely from asymptomatic illness
to a congenital syndrome with microcephaly, jaundice, hepatosplenomegaly and
petechiae. Infants who are asymptomatic at birth may still present with
sensorineural hearing loss, mental retardation and neuromuscular defects at a
later age. We report a full term, small-for-gestational age neonate with
congenital CMV infection who presented with unusual clinical features,
including choanal atresia, digital hypoplasia, simian crease, blueberry muffin
rash, cortical atrophy and hemiparesis.