Affiliations: Department of Pediatric Critical Care Medicine, St.
Vincent Mercy Children's Hospital, Toledo, OH, USA | Department of Pediatric Infectious Diseases, Michigan
State University, Hurley Medical Center, Flint, MI, USA
Note:  Correspondence: Rashed A. Hasan, MD, Department of Pediatric
Critical Care Medicine, St. Vincent Mercy Children's Hospital, Toledo, OH,
USA. E-mail: [email protected]
Abstract: Disseminated herpes simplex virus (HSV) infection is a well
recognized condition in infants and children. However, the diagnosis of
isolated HSV pneumonia, without evidence of other organ involvement, in this
population is rare. We present a case series of isolated HSV pneumonia in four
patients, all of which survived this acute illness with normal neurological
outcome. Clinical features, diagnostic approaches, intensive care management,
and antiviral drug therapy are reviewed.