Congenital cytomegalovirus infection with multiorgan involvement
and coarctation of aorta with aortic thrombi and corpus callosal agenesis: A
causal association?
Affiliations: Department of Pediatrics, Institute of Postgraduate
Medical Education and Research, Kolkata, India | Department of Pediatric Cardiology, Institute of
Postgraduate Medical Education and Research, Kolkata, India
Abstract: Congenital human cytomegalovirus (HCMV) infection is a well-known
entity. There are infrequent reports of HCMV infection causing endothelial
damage leading to aortic thrombi and coarctation of aorta. Also, association of
congenital HCMV infection with corpus colossal agenesis has been reported very
infrequently. We describe such a case with HCMV infection with multiorgan
involvement and two unusual features of aortic pathology and corpus colossal
agenesis in the absence of other more frequently described central nervous
system findings.
Keywords: Cytomegalovirus, coarctation of aorta, aortic thrombi, corpus colossal agenesis