Affiliations: Department of Infectious Diseases, University Medical
Centre Ljubljana, Ljubljana, Slovenia | Institute of Microbiology and Immunology, Medical
Faculty, University of Ljubljana, Ljubljana, Slovenia
Note: [] Correspondence: Maja Arnež, MD, PhD, University Medical
Centre Ljubljana, Department of Infectious Diseases, Japljeva 2, 1525
Ljubljana, Slovenia. Tel.: +3861 522 2110; Fax: +3861 522 2456; E-mail:
[email protected]
Abstract: Slovenia is a highly endemic region for Lyme borreliosis. We present
three patients with multiple erythema migrans and simultaneous isolation of
Borrelia burgdorferi sensu lato from blood and cerebrospinal fluid. The
patients were identified in a prospective study on children with multiple
erythema migrans in whom central nervous system involvement was actively
searched. The patients had no obvious symptoms and signs of central nervous
system involvement. At the end of 14-day treatment with ceftriaxone the
patients were free of signs and symptoms of borrelial infection. We stressed
the importance of cerebrospinal fluid investigations and early appropriate
antibiotic treatment in these patients.
