Affiliations: USC Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA | The Vision Center, Children's Hospital Los Angeles, Los Angeles, CA, USA
Note:  Corresponding author: Sudha Nallasamy, MD, Children's Hospital Los Angeles, 4650 Sunset Blvd., MS #88, Los Angeles, CA 90027, USA. Tel.: +1 323-361-4510; Fax: +1 323-361-7993; E-mail: [email protected]
Abstract: Genetic diseases of the macula and choroid have various inheritance patterns and varying degrees of impact on vision. Herein, we review the literature including most recent advances in the understanding of the genetics of these diseases. Although many of these disorders have limited treatment options, knowledge of inheritance patterns can aid in early detection and with close monitoring can help the ophthalmologist preserve as much vision as possible (for example with early treatment of choroidal neovascularization).