Struthers Parkinson’s Center, Golden Valley, MN, USA
Methodist Hospital, St Louis Park, MN, USA
Health Partners Institute, Bloomington, MN, USA
Correspondence to: Martha A. Nance, MD, Struthers Parkinson’s Center, 6701 Country Club Drive, Golden Valley, MN 55427, USA. Tel.: +1 952 993 6592; Fax: +1 952 993 2245; E-mail: martha.nanc[email protected].
Abstract: Background:Patients hospitalized with Parkinson’s disease (PD) require timely delivery of carbidopa-levodopa (C/L) medication. Ill-timed administration of C/L doses is associated with greater morbidity and longer lengths of stay. Objective:To understand the barriers to timely C/L administration, and implement strategies to improve the administration of the drug to hospitalized PD patients. Methods:Several key strategies were employed in 2015 to improve the timely delivery of C/L doses: 1. three kinds of nursing alert in the electronic medical record (EMR); 2. staff in-service education; 3. stocking immediate-release C/L into automated medication dispensing machines on key hospital units; 4. reports to nurse unit managers on timeliness of C/L administration; and 5. reconciliation of inpatient and outpatient levodopa orders by the hospital pharmacist upon admission. The primary outcome was the percent of C/L doses administered within 60, 30, and 15 minutes of scheduled time. Results:Our urban hospital, affiliated with a Parkinson’s Foundation Center of Excellence, had 5,939 C/L administrations in 2018. There was sustained improvement in timely delivery of doses, from 89.3% in 2012 to 96.5% in 2018 (within 60 minutes of the scheduled time), 65.5% to 86.4% (30 minutes), and 42.3% to 71.1% (15 minutes) (all p < 0.001). Conclusions:With multifaceted but relatively simple measures, we were able to “change the culture” so that hospitalized patients with Parkinson’s disease receive levodopa on time.
Keywords: Parkinson’s disease, levodopa, quality improvement, nursing care, hospital