Affiliations: [a] Department of Neurology, University of Colorado, Aurora, CO, USA
| [b] Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
| [c] Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
University of Delaware, Newark, DE, USA
| [e] Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA, USA
Correspondence to: Michelle Fullard, MD, MS, Department of Neurology, University of Colorado, Mail Stop B185, 12631 E 17th Avenue, Aurora, CO 80045, USA. Tel.: +1 303 724 8295; Fax: +1 303 724 2212; E-mail: [email protected].
Abstract: Background:Advances in the treatment of Parkinson’s disease (PD) have allowed for improvements in mortality and quality survival, making the management of comorbid conditions of aging, such as osteoarthritis, crucial. Objective:To determine the extent to which PD impacts hospitalization outcomes after an elective orthopedic procedure. Methods:This retrospective cohort study used data from the National Readmissions Database and included adults ages 40 and above with and without PD. Primary outcomes included length of stay of the index admission, discharge disposition and 30-day readmission. Logistic regression was used to compare the odds of readmission for PD patients compared to non-PD. Clinical conditions associated with readmission were compared between the two groups. Results:A total of 4,781 subjects with PD and 947,475 subjects without PD met inclusion criteria. Length of stay (LOS) during the index admission was longer for PD patients. PD patients were much more likely to be discharged to inpatient post-acute care (49.3% vs 26.2%) while non-PD subjects were more likely to be discharged home with (31.9% [PD] vs 44.8% [non-PD]) or without home health (18.7% [PD] vs 28.9% [non-PD]). A total of 271 PD patients (5.66%) and 28,079 non-PD patients (2.96%) were readmitted within 30 days following surgery. After adjusting for age, sex, socioeconomic status, expected payer, comorbidities, index admission LOS, year and discharge disposition, PD subjects were 31% more likely to be readmitted than non-PD subjects (AOR 1.31, 1.07–1.62). Conclusions:Parkinson’s disease patients were readmitted more often than non-PD patients, although the rate of readmission was still low.
Keywords: Parkinson’s disease, cohort studies, arthroplasty, knee replacement, hip