Affiliations: [a] Faculty of Medical Science, Newcastle University, Newcastle upon Tyne, UK
| [b] Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK
| [c] Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK
| [d] School of Medicine & Menzies Health Institute Queensland, Griffith University, Australia
| [e] Newcastle Institute for Ageing, Newcastle University, Newcastle upon Tyne, UK
| [f] AGE Group, Newcastle University, Newcastle upon Tyne, UK
Department of Clinical Neurosciences, Cambridge Centre for Brain Repair, Cambridge, UK
Correspondence to: Rhys Gravell, Faculty of Medicine, Newcastle University, Newcastle upon Tyne, NE4 5PL, UK. E-mail: [email protected].
Abstract: Recent guidance by the National Institute for Health and Care Excellence (NICE) focuses on the management of people with multimorbidity, including Parkinson’s disease (PD). To date there has been little exploration of this in neurodegenerative diseases. This study aimed to explore the associations between multimorbidity, motor severity and quality of life (QoL) in early PD. Regression analyses determined whether multimorbidity was significantly associated with disease severity and QoL. Multimorbidity was a small but significant predictor of QoL in people with incident PD, but not motor severity, suggesting that they may benefit from a tailored multidisciplinary approach to care.
Keywords: Multimorbidity, Parkinson’s disease, quality of life, motor severity