Affiliations: Department of Neurology, Donders Institute for Brain, Cognition and Behavior, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands | Sleep Medicine Centre Kempenhaeghe, Heeze, The Netherlands | Department of Neurology, University Hospital Zurich, Zurich, Switzerland
Note:  Correspondence to: Sebastiaan Overeem, MD, PhD, Department of Neurology, Donders Institute for Brain, Cognition and Behavior, Radboud University Nijmegen Medical Centre, PO Box 9101, HB Nijmegen 6500, The Netherlands. Tel.: +31 24 361 52 02; E-mail: [email protected]
Abstract: Some patients with Parkinson's disease (PD) reportedly experience ‘sleep benefit’: an improved motor functioning upon awaking in the morning. In this questionnaire study, 114 out of 243 consecutive outpatients with PD (46.9%) subjectively experienced sleep benefit. Among those patients that regularly took an afternoon nap, 33.7% experienced sleep benefit after the nap as well. Between patients with and without sleep benefit, there were no differences in demographic or clinical variables, including age, disease duration, dopaminergic treatment, and nocturnal sleep quality. Sleep benefit remains an intriguing but elusive phenomenon, which deserves renewed attention and further research.
Keywords: Sleep, Parkinson's disease, nap, questionnaires, pittsburgh sleep quality index