You are viewing a javascript disabled version of the site. Please enable Javascript for this site to function properly.
Go to headerGo to navigationGo to searchGo to contentsGo to footer
In content section. Select this link to jump to navigation

Cognitive Deficits Associated with Sleep Apnea in Myotonic Dystrophy Type 1


Although sleep-disordered breathing and cognitive impairment are common features of patients with myotonic dystrophy type 1 (DM1), little is known about their relationship. Forty-three adult DM1 patients underwent 2 sequential polysomnographic sessions and a neuropsychological test battery (intellectual functioning, attention, language, memory, and executive functions). Lower scores in attention, vigilance, and executive functioning tests were associated with higher number of apneic/hypopneic episodes per hour of sleep and longer total sleep time at an oxyhemoglobin saturation of less than 90%. Results suggest a potential role for nighttime breathing problems in the cognitive impairment often observed in DM1 patients.