Vaccination is preventing development of placental pathologies in SARS-CoV-2 infected pregnant patients

Article type: Research Article

Authors: Ozer, E.^{a; *} | Cagliyan, E.^b | Cagaptay, S.^a

Affiliations: [a] Department of Pathology, Dokuz Eylul University Hospital, Izmir, Turkey | [b] Department of Obstetrics & Gynecology, Dokuz Eylul University Hospital, Izmir, Turkey

Correspondence: [*] Address for correspondence: Erdener Ozer, MD, PhD, Department of Pathology, Dokuz Eylul University School of Medicine, Balcova, Izmir, 35340 Turkey. Tel.: +90 532 341 0535; E-mail: [email protected].

Abstract: INTRODUCTION:The coronavirus disease (COVID-19) has created a serious health problem in pregnant people. We aimed to address whether vaccination can prevent development of placental disease in SARS-CoV-2 infected mothers. METHODS:We reported the pathology findings obtained from routine histopathological examination of placentas of overall 38 cases. RESULTS:We found low prevalence of placental pathology in vaccinated pregnant people with active SARS-CoV-2 infection in comparison to those unvaccinated cases. CONCLUSION:Based on our findings, SARS-CoV-2 vaccination can prevent development of placental pathological lesions and may lower the risk of serious illness in pregnant people.

Keywords: COVID-19, placenta, pregnancy, SARS-CoV-2, vaccination

DOI: 10.3233/NPM-221141

Journal: Journal of Neonatal-Perinatal Medicine, vol. 16, no. 2, pp. 235-237, 2023