Affiliations: [a] Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, San Camillo-Forlanini Hospital, Rome | [b] Department of Obstetrics and Gynaecology Campus Bio-Medico University of Rome, Italy
| [c] Department of Biomedicine and Prevention, Section of Gynecology and Obstetrics, University of Rome Tor Vergata, Rome, Italy
Address for correspondence: Stella Capriglione, MD, Department of Obstetrics and Gynecology, University of Rome “Campus Bio-Medico”, Via Alvaro del Portillo, 200 –00128 Rome, Italy. Tel.: +39 3452572851; Fax: +39 06 22541456; E-mail: [email protected].
Abstract: Hemorrhagic cystitis is generally a benign self-limited disorder, however there are some severe cases which are associated to a significant blood loss. The etiology may be either bacterial, viral or chemical in origin; though the cause is not identified in most of the cases. Immunocompromised patients or patients who have undergone chemotherapy or radiation constitute the highest risk group. There are only a few articles about hemorrhagic cystitis in pregnancy, frequently associated with preterm labor. We describe, for the first time in literature, one patient with a clinical status of hematuria in two consequent pregnancies, without any identified cause and a medical history negative for recurrent or hemorrhagic cystitis and we report an overview of literature concerning this topic.