Congenital parvovirus B19 infection associated with perinatal stroke

Article type: Research Article

Authors: Siebert, Stephanie | Eis-Hübinger, Anna Maria | Müller, Andreas | Bartmann, Peter | Heep, Axel

Affiliations: Department of Neonatology, University of Bonn, Bonn, Germany | Department of Virology, University of Bonn, Bonn, Germany

Note: [] Corresponding author: Dr. Stephanie Siebert, Department of Neonatology, Adenauerallee 119, D-53113 Bonn, Germany. Tel.: +49 228 287 33408; Fax: +49 228 287 33296; E-mail: stephanie. [email protected]

Abstract: We report a case of left hemispheric cerebral stroke and occlusion of right axillary artery in a newborn with fetal last trimester parvovirus B19 infection detected by polymerase chain reaction for viral DNA. Thromboembolic occlusion of cervical and cerebral arteries was demonstrated on MRI. Excluding vasculitis or prothrombotic condition, data suggest neonatal stroke arising from the congenital parvovirus B19 infection.

Keywords: Parvovirus, neonate, thromboembolic event, stroke

DOI: 10.3233/NPM-2010-0108

Journal: Journal of Neonatal-Perinatal Medicine, vol. 3, no. 2, pp. 153-156, 2010