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Article type: Review Article
Authors: Rosen, Allyson C.a; b; * | Lavacot, James A.a | Klee, Victoriac | Luria, Yuvala; d | Rumbaugh, Maliae
Affiliations: [a] VA Medical Center-Palo Alto, Palo Alto, CA, USA | [b] Stanford School of Medicine, Stanford, CA, USA | [c] The Ohio State University College of Medicine, Columbus, OH, USA | [d] Neuvivo, Palo Alto, CA, USA | [e] Indiana University School of Medicine, Indianapolis, IN, USA
Correspondence: [*] Correspondence to: Allyson Rosen, PhD, ABPP-CN, Mental Illness Research, Education and Clinical Center (MIRECC), Palo Alto VA Medical Center, 3801 Miranda Ave (151Y), Palo Alto, CA 94304-1207, USA. E-mail: [email protected].
Abstract: Ethics Review began a decade ago with a mission to identify ethical concerns that hold back innovation and to promote solutions that would move the field forward. Over this time, blood biomarkers for brain pathology and medications that treat that pathology promise to transform research and care. A central problem is that the evidence needed to guide test interpretation and practice is accumulating and there are unanswered questions. At the same time, people living with and at risk for dementia want access to their test results and involvement in their care. We promote dialog among diverse people across many institutions through collaboration with the Advisory Group on Risk Evidence Education for Dementia (AGREEDementia.org). Over the years Ethics Review continues to publish these dialogs and solutions to overcome the paralysis of indecision and ethical concerns.
Keywords: Alzheimer’s disease, amyloid-beta, blood biomarker, diagnostics, ethics
DOI: 10.3233/JAD-240634
Journal: Journal of Alzheimer's Disease, vol. 100, no. s1, pp. S283-S290, 2024
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