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Lifetime History of Depression Predicts Increased Amyloid-β Accumulation in Patients with Mild Cognitive Impairment

[Journal of Alzheimers Disease 45(3), 2015, 907-919.DOI 10.3233/JAD-142931]

The ADNI reported AV-45 mean values on figure 2 (page 912) and table 2 (page 914) were raw AV-45 values, and should be changed to AV-45 SUVR values.

Therefore, the regional AV-45 SUVR values on Figure 2 and table 2 have changed in the corrected Figure 2 and Table 2 below.


Table II

Comparison of region-of-interest based AV-45 SUVR between aMCI patients with a lifetime history of major depression and aMCI patients without a lifetime history of major depression

Regions of interestaMCI-LMD (n = 39)aMCI+LMD (n = 39)F-valuep-value
Frontal ∗1.320.211.390.274.290.04 ∗

Abbreviations: aMCI = amnestic mild cognitive impairment; aMCI+LMD = aMCI with a lifetime history of major depression; aMCI-LMD = aMCI without any lifetime history of major depression; ANCOVA = analysis of covariance; AV-45 SUVR =18F-Florbetapir standardized uptake value ratio with a reference to cerebellar grey matter.