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Article type: Review Article
Authors: Froestl, Wolfgang; * | Pfeifer, Andrea | Muhs, Andreas
Affiliations: AC Immune SA, EPFL, Lausanne, Switzerland
Correspondence: [*] Correspondence to: Dr. Wolfgang Froestl, AC Immune SA, EPFL, Innovation Park, Building B, CH-1015 Lausanne, Switzerland. Tel.: +41 21 693 91 43; Fax: +41 21 693 91 20; E-mail: [email protected].
Abstract: Scientists working in the field of Alzheimer's disease and, in particular, cognitive enhancers, are very productive. The review “Drugs interacting with Targets other than Receptors or Enzymes. Disease-modifying Drugs” was accepted in October 2012. In the last 20 months, new targets for the potential treatment of Alzheimer's disease were identified. Enormous progress was realized in the pharmacological characterization of natural products with cognitive enhancing properties. This review covers the evolution of research in this field through May 2014.
Keywords: Amyloid-β aggregation inhibitors, antibodies, antioxidants, cognitive enhancers, metal chelators, natural products, nootropics, peptides, psychostimulants, stem cells, tau, vaccines
DOI: 10.3233/JAD-141206
Journal: Journal of Alzheimer's Disease, vol. 42, no. 4, pp. 1079-1149, 2014
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