Affiliations: AC Immune SA, EPFL, Lausanne, Switzerland
Correspondence:
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Correspondence to: Dr. Wolfgang Froestl, AC Immune SA, EPFL, Innovation Park, Building B, CH-1015 Lausanne, Switzerland. Tel.: +41 21 693 91 43; Fax: +41 21 693 91 20; E-mail: [email protected].
Abstract: Scientists working in the field of Alzheimer's disease and, in particular, cognitive enhancers are very productive. The review on Drugs interacting with Enzymes was accepted in August 2012. However, this field is very dynamic. New potential targets for the treatment of Alzheimer's disease were identified. This update describes drugs interacting with 60 enzymes versus 43 enzymes in the first paper. Some compounds progressed in their development, while many others were discontinued. The present review covers the evolution of research in this field through April 2014.
