Increased Dendrite Branching in AβPP/PS1 Mice and Elongation of Dendrite Arbors by Fasudil Administration

Article type: Short Communication

Authors: Couch, Brian A.^a | DeMarco, George J.^b | Gourley, Shannon L.^{a; c} | Koleske, Anthony J.^{a; d; e; *}

Affiliations: [a] Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA | [b] Section of Comparative Medicine, Yale University, New Haven, CT, USA | [c] Department of Psychiatry, Yale University, New Haven, CT, USA | [d] Department of Neurobiology, Yale University, New Haven, CT, USA | [e] Interdepartmental Neuroscience Program, Yale University, New Haven, CT, USA

Correspondence: [*] Correspondence to: Anthony J. Koleske, Department of Molecular Biophysics and Biochemistry, Yale University, 333 Cedar Street, SHM CE-31, New Haven, Connecticut 06520, USA. Tel.: +1 203 785 5624; Fax: +1 203 785 7979; E-mail: [email protected].

Note: [] Handling Associate Editor: Shu G. Chen

Keywords: Amyloid-β protein precursor, dendrites, fasudil, hippocampus, intracerebroventricular infusion, presenilin-1, Rho GTPase, Rho kinase

DOI: 10.3233/JAD-2010-091114

Journal: Journal of Alzheimer's Disease, vol. 20, no. 4, pp. 1003-1008, 2010