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Article type: Short Communication
Authors: Hoffmann, Michael; * | Muniz, Juan | Carroll, Elizabeth | De Villasante, Jorge
Affiliations: Department of Neurology, University of South Florida and James A Haley Veteran's Administration Hospital, Tampa, FL, USA
Correspondence: [*] Corresponding author: Michael Hoffmann MD, Associate Dean and Professor of Neurology and Neurosurgery, University of South Florida and James A Haley VA Hospital, 13000 Bruce B Down's Blvd, Tampa, FL 33612, USA. E-mail: [email protected].
Abstract: A sixty-two year old man, with a background of Alzheimer's disease for the past three years, acutely presented with imbalance, headaches, and dizziness. Examination revealed a profound frontal disinhibited and dysexecutive syndrome and brain imaging notable for leptomeningeal enhancement; laboratory data confirmed cryptococcal meningitis. Four months after treatment, the patient was normal neurologically, cognitively and neuroradiologically. The specific cognitive impairment and neuroradiological findings may be clues to differing dementia etiologies.
Keywords: Cryptococcal meningitis, dementia, frontal syndrome
DOI: 10.3233/JAD-2009-0985
Journal: Journal of Alzheimer's Disease, vol. 16, no. 3, pp. 517-520, 2009
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