Amyloid-β: redox-metal chelator and antioxidant

Issue title: Challenging Views of Alzheimer's disease

Article type: Research Article

Authors: Atwood, C.S.^{a; *} | Robinson, S.R.^b | Smith, M.A.^a

Affiliations: [a] Institute of Pathology, Case Western Reserve University, Cleveland, OH 44106, USA | [b] Department of Psychology, Monash University, Clayton, Victoria, 3800, Australia

Correspondence: [*] Corresponding author. Craig S. Atwood, Ph.D., Institute of Pathology, Case Western Reserve University, 2085 Adelbert Rd., Cleveland, OH 44106, USA. Tel.: +1 216 368 5903; Fax: +1 216 368 8964; E-mail: [email protected].

Keywords: Alzheimer's disease, Aβ, AβPP expression, acute phase response, metal ions, glutamine synthetase, iron, copper, oxidation, oxidative stress, injury, head trauma, chelation, neurotrophic, neurotoxic

DOI: 10.3233/JAD-2002-4310

Journal: Journal of Alzheimer's Disease, vol. 4, no. 3, pp. 203-214, 2002