For 80 years, Annual Reviews has been synthesizing the literature to help scientists keep up with the wealth of scientific research that is published each year. Our content has traditionally been delivered online and in print as long-form review articles, but with scientists more pressured than ever, we have looked into mobile platforms for new ways to fit information into readers' workflows. We asked ourselves, How are our users changing? How do their needs or habits differ? What is important to them? By leveraging our core role and strengths, Annual Reviews strives to be innovative in our approach to solving readers' future problems. This article looks at our product development and innovation processes and experiences, with examples of lessons learned and hints on where we are going next.