Affiliations: [a] Research Center for Health Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
| [b] Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran
Correspondence:
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Corresponding author: Ahmad Maghsoudi, Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.E-mail: [email protected]
Abstract: INTRODUCTION:Breast Cancer (BC) is the most prevalent cancer and the second leading cause of cancer-related death among Iranian women. A valid estimation of the 5-year survival rate can improve the current BC treatment programs. The present study aimed to assess the 5-year survival rate through a systematic review of published studies. METHODS:A systematic search of Medline/PubMed, Scopus, and Science direct as well as Iranian databases was conducted to identify the original articles evaluating the 5-year survival rate of BC among women in Iran. Random effects model was used to estimate the pooled 5-year survival rate. The eligible articles were analyzed using the Stata software. RESULTS:Our comprehensive literature search identified 11 eligible articles 2 of which were excluded due to reporting the results of a single study. The remaining 9 articles that contained 4815 women diagnosed with BC during 1991–2014 were included in the meta-analysis. The combined 5-year survival rate of BC was estimated to be 67.60%. DISCUSSION/CONCLUSION:The survival rate of BC was relatively low in Iran compared to developed countries. Hence, more effective measures have to be taken to increase these patients’ survival.
Keywords: Survival rate, breast cancer, systematic review, meta-analysis, Iran
DOI: 10.3233/BD-160244
Journal: Breast Disease, vol. 37, no. 2, pp. 63-68, 2017
